Emory Vaccine Center
Department of Pathology and Laboratory Medicine, Emory University School of Medicine
Division of Pathology, Yerkes National Primate Research Center
Emory Center for AIDS Research
Dr. Villinger is a Professor in the Department of Pathology and Laboratory Medicine in the Emory School of Medicine and the Associate Director for the Yerkes Division of Pathology. He received his DVM and PhD in 1986 from the University of Zurich in Switzerland. He joined Emory University as a postdoctoral fellow in 1989 and joined the faculty in the Department of Pathology and Laboratory Medicine in 1995. In September 2007, he was appointed as the Associate Director for the Division of Pathology at the Yerkes National Primate Research Center.
Dr. Villinger’s research interests are focused on nonhuman primate models of infectious diseases and modulation of immune responses in health or disease using nonhuman primate models. One major area of work focuses on the modulation of immune responses in the context of Simian immunodeficiency virus, using a variety of immunomodulatory factors such as cytokines as well as adoptive transfer of in vitro expanded CD4+ T cells. Another area of work is the evaluation of efficacy and delivery methods of monoclonal based microbicides for the prevention of vaginal transmission of simian/human immunodeficiency virus. Other models of human infection tested in nonhuman primates include dengue, and in development, Tuberculosis and Listeria monocytogenes. In addition, Dr. Villinger directs the NCRR funded “Resource for nonhuman primate immune reagents” (http://pathology.emory.edu/Villinger/index.htm) which handles a repository for primate immune related cDNA clones, expression constructs and the production and testing of monkey recombinant cytokines and antagonists to modulate immune responses in vivo, in the context of immunization and/or infection. In collaboration with GA Tech, my lab is also exploring novel techniques for imaging infectious agents in real time to monitor viral dynamics in vivo.