basic immunology + virology
The term basic, when applied to research in immunology, virology,
or any other scientific field, may mislead some into thinking
it synonymous with elementary. But basic research is anything
but simple; on the contrary, basic research is what expands the
frontiers of our knowledge by answering questions about how things
work. With regard to immunology and virology, basic research
explains the cellular and molecular processes of the immune system
and the mechanisms by which viruses undermine those processes.
Basic
immunology and virology are crucial to the EVC’s
research program; the findings that stem from this research form
the foundation upon which other scientists build vaccine strategies
and methods for assessing their success. Without basic science,
the development of vaccines would have to rely on fortunate happenstance
instead of genuine understanding.
A major thrust of the basic
virology research at the EVC is answering the question of why
and how certain viruses establish chronic,
latent infections that so far are beyond our ability to cure.
HIV, hepatitis C virus, and herpesviruses are common examples
of viruses that cause chronic infections.
Investigators:
Rafi Ahmed, Ph.D.
John Altman, Ph.D.
Joshy Jacob, Ph.D.
Robert Mittler, Ph.D.
Bali Pulendran, Ph.D.
Samuel Speck, Ph.D. |