Area of Research: Basic Immunology/Virology; Immune system ontogeny and phylogeny My colleagues and I study hemopoietic stem cell differentiation along lymphoid and myeloid pathways. This information on normal development of cells belonging to the immune system is used for analysis and treatment of individuals with immunodeficiencies and with malignancies of the immune system. Many of the activities in this laboratory are devoted to the study of the life history of B and T cells, and how their development may go awry. Current research focuses on the role of immunoglobulin and non-immunoglobulin genes in B cell development, and evolution of the adaptive immune system. Max D. Cooper (b. 1933), Georgia Research Alliance Eminent Scholar, Professor of Pathology and Laboratory Medicine and Emory Vaccine Center, Emory University School of Medicine. Dr. Cooper graduated from Tulane University Medical School in 1957. While at the University of Minnesota from 1963-1967 he worked with Robert A. Good to establish the dual nature of the immune system. With UAB graduate student Paul Kincade, he discovered isotype switching by IgM-producing B cells. While on sabbatical at University College London in 1974, he worked with Martin Raff and John Owen to identify the bone marrow and fetal liver precursors of B cells. He is involved in clinical studies, particularly in relation to the cell differentiation abnormalities in immunodeficiency diseases and lymphoid malignancies. He is an editor of several immunological journals, past president of the Clinical Immunology Society and of the American Association of Immunologists, and a Georgia Research Alliance Eminent Scholar. Outside interests include sailing, cooking, reading and travel.
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